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3 Derek Angus et al., “Epidemiology of Severe Sepsis in the United States: Analysis of Incidence, Outcome, and Associated Costs of Care”, Critical Care Medicine 29 (2001), 1303–1310.

4 Brian Beutler et al., “Passive Immunization Against Cachectin/ Tumor Necrosis Factor Protects Mice from Lethal Effect of Endotoxin”, Science 229 (1985), 869–871.

5 Kevin Tracey et al., “Shock and Tissue Injury Induced by Recombinant Human Cachectin”, Science 234 (1986), 470–474.

6 Kevin Tracey et al., “Anti-cachectin/TNF Monoclonal Antibodies Prevent Septic Shock During Lethal Bacteremia”, Nature 330 (1987), 662–464.

7 Huan Wang et al., “HMG-1 as a Late Mediator of Endotoxin Lethality in Mice”, Science 285 (1999), 248–251; Huan Yang et al., “Reversing Established Sepsis with Antagonists of Endogenous High-Mobility Group Box 1”, Proceedings of the National Academy of Sciences 101 (2004), 296–301.

8 L. V. Borovikova et al., “Vagus Nerve Stimulation Attenuates the Systemic Inflammatory Response to Endotoxin”, Nature 405 (2000), 458–462.

9 Hong Wang et al., “Nicotinic Acetylcholine Receptor alpha/ Subunit Is an Essen tial Regulator of Inflammation”, Nature 421 (2003), 384388; Kevin Tracey, “The Inflammatory Reflex”, Nature 420 (2002), 853–859.

10 Thomas Bernik et al., “Pharmacological Stimulation of the Cholinergic Anti inflammatory Pathway”, Journal of Experimental Medicine 195 (2002), 781–788; H. Wang et al., “Cholinergic Agonists Inhibit HMGB1 Release and Improve Survival in Experimental Sepsis”, Nature Medicine 10 (2004), 1216–1221.

11 Greta Van den Berghe et al., “Intensive Insulin Therapy in Critically Ill Patients”, New England Journal of Medicine 345 (2001), 1359–1367.

12 Greg Martin et al., “The Epidemiology of Sepsis in the United States from 1979 Through 2000”, New England Journal of Medicine 348 (2003), 1546–1554.

13 Derek Angus, “Sepsis on the Rise in the United States”, 32nd annual Critical Care Congress, San Antonio, Texas, 2003; Derek Angus et al., “Epidemiology of Severe Sepsis in the United States: Analysis of Incidence, Outcome, and Associated Costs of Care”, Critical Care Medicine 29 (2001), 1303–1310.

14 Garth Ehrlich et al., “Device-Related Infections of Prosthetic Devices in the United States, Table 1 in Engineering Approaches for the Detection and Control of Orthopaedic Biofilm Infections”, Clinical Orthopaedics and Related Research 2005 (437), 59–66. Примечание. В указанной таблице не учтены искусственные хрусталики глаза, которых в США ежегодно имплантируют от одного до двух миллионов, что в 7-10 % случаев приводит к развитию инфекций. Источник: A. Hornblass et al., “Current Techniques of Enucleation: A Survey of 5,439 Intraorbital Implants and a Review of the Literature”, Ophthalmic Plastic and Reconstructive Surgery 11 (1995), 77–86.